What to Know About Sucralose (2024)

We know that to maintain a healthy diet it’s important to limit the amount of sugar and sweets that we eat. But what about artificial sweeteners? Sugar alternatives are popular among those who want to watch their carbohydrate and calorie intake.

The newest artificial sweetener is sucralose, also known as Splenda. Here’s what you need to know about this artificial sweetener.

What Is Sucralose?

Sucralose is marketed as Splenda, an artificial sweetener that often comes in a yellow packet. The difference between Splenda and other sweeteners, like aspartame (Equal) and saccharin (Sweet’N Low), is that it’s actually made from real sugar. This gives it a taste that is generally more preferable compared to other artificial sweeteners.

Sucralose is chemically changed so that it’s 600 times sweeter than real sugar with almost no calories. It doesn’t leave an aftertaste in your mouth, so sucralose is used in foods like yogurt, candy, ice cream, and soda.

In addition to being changed for taste, sucralose is also altered so that most of it passes through your body instead of being stored to later use as energy. To make sucralose almost calorie-free, some naturally occurring parts of the sugar molecule, called hydroxyl, are swapped out for chlorine.

Is Sucralose Healthy?

Since its introduction around 20 years ago, millions of people have turned to Splenda as a way to enjoy some of their favorite sweets with fewer calories. By making a simple swap of sucralose for sugar, it can help you limit calorie intake.

This can be especially helpful for people with diabetes who need to monitor their sugar intake. Splenda sweetens foods and drinks but doesn’t make your blood sugar levels to spike the way that regular sugar does.

Sucralose and weight. While sweeteners like Splenda are low in calories, that doesn’t necessarily mean that they help you lose weight. Some studies show that people who replace sugar with artificial sweeteners may weigh a pound or so less on average.

The National Weight Control Registry (NWCR) is an ongoing study that tracks the habits of people who have lost 30 pounds or more and are able to keep it off. Many people in this study say that drinking beverages with sucralose or other artificial sweeteners helps them to better count calories and keep off weight.

Other studies, however, suggest that people who drink diet sodas sweetened with sucralose actually end up taking in more calories than those who drink sodas with regular sugar. This can result in higher overall body weight. Sucralose may stimulate your appetite, making you eat more. It’s important to note, however, that this research hasn’t been fully proven.

Sucralose and gut health. Your gastrointestinal tract (GI), or microbiome, is home to lots of different kinds of helpful bacteria. These bacteria help your body to maintain a healthy immune system. Some studies have shown that sucralose can change your gut microbiome by lowering the number of good bacteria by half.

Research done on animals shows that sucralose can also increase inflammation in the body. Over time, inflammation can lead to problems like obesity and diabetes. Since these studies have only been done on rodents, more research needs to be done to understand how humans can be affected by sucralose.

Is Sucralose Safe?

Sucralose is an approved ingredient in many countries around the world. You may find sucralose in items like:

  • Packaged foods
  • Ready-made meals
  • Desserts
  • Chewing gum
  • Toothpaste
  • Drinks
  • Cakes

Studies in both the U.S. and the U.K. have found that sweeteners like Splenda don’t cause cancer, which was once a concern. The FDA has done extensive testing on animals to make sure that Splenda does not have any neurological, carcinogenic, or reproductive effects.

Even though sucralose is considered to be safe by the FDA and other international organizations, you should try to be mindful when it comes to artificial sweeteners. There are still studies being done on artificial sweeteners and how they affect our health. Read the labels of products you regularly eat, drink, or use to see if they contain sucralose or other sweeteners.

Other studies suggest that you can avoid any potential risks that artificial sweeteners may have by changing up the ones that you consume now and then. If you really like adding Splenda to your coffee or baked goods, try using other sweeteners or real sugar once in a while. The American Dental Association (ADA) even suggests that mixing sweeteners can increase overall sweetness.

Remember that sugar in small amounts is okay. Sweeteners like sucralose can have some benefits, but you shouldn’t demonize sugar if it doesn’t have a negative effect on your health when it's used in moderation.

What to Know About Sucralose (2024)

FAQs

What are the risks of sucralose? ›

Some studies have shown that sucralose can change your gut microbiome by lowering the number of good bacteria by half. Research done on animals shows that sucralose can also increase inflammation in the body. Over time, inflammation can lead to problems like obesity and diabetes.

How much sucralose per day is safe? ›

The daily ingestion level of sucralose is fixed at 15 mg/kg/d by EFSC. Persons taking various medications, children, and infants are not restricted from the use of sucralose. Sucralose does not show any carcinogenic activity even when the levels of exposure are much higher than normal levels of ingestion.

What is the new news about sucralose? ›

New research suggests that sucralose-6-acetate, a chemical found in artificial sweeteners, is “genotoxic,” meaning it could cause DNA damage. The study findings show that sucralose harms gut health and may lead to oxidative stress, inflammation, and cancer.

What is the safest artificial sweetener to use? ›

The FDA has determined these sweeteners are safe, or not toxic, for the general public:
  • Aspartame.
  • Acesulfame potassium (Ace-K)
  • Sucralose.
  • Neotame.
  • Advantame.
  • Saccharin.
Jun 11, 2023

What is worse sugar or sucralose? ›

“Really, both sugar and artificial sweeteners are a problem for your health,” says functional medicine specialist Melissa Young, MD. “But if we're comparing what's worse, artificial sweeteners are far worse than sugar.”

Is sucralose banned in Europe? ›

Sucralose is authorised in the EU for food use with exception for foods for young children.

What does sucralose do to your gut? ›

There's some conflicting research on whether sucralose kills gut bacteria, but it does appear that sucralose can disrupt the balance of gut bacteria. Some studies show that even consuming sucralose at levels thought to be safe causes changes in gut bacteria.

How to flush sucralose out of your system? ›

Flushing Sucralose From Your System

Consuming fiber-rich foods like fruits, vegetables, and whole grains can also aid in digestion and help your body eliminate sucralose. At the same time, moderate exercise can stimulate digestion and promote the excretion of sucralose.

Should I stop using sucralose? ›

Sucralose is an artificial sweetener that is generally considered safe when enjoyed in moderation. However, research on its long-term effects has turned up mixed results. Excessive amounts of added sugar can have harmful effects on your metabolism and overall health ( 1 ).

What is the most unhealthy artificial sweetener? ›

The worst of the worst culprits include aspartame (found in Equal and NutraSweet), sucralose (found in Splenda), and Saccharin (found in Sweet 'N Low). Many people who cut artificial sugars out of their diets report the improvement of many health problems including migraines, depression, IBS, weight gain, and more.

Which is safer sucralose or stevia? ›

According to the Mayo Clinic, neither of the two should be consumed in excess. However, they are extremely useful for overcoming a craving for sugar. Stevia should be considered the more natural option for those looking for a healthier inclusion in food supplements.

What is the least harmful sugar substitute? ›

Stevia and monk fruit are both naturally derived from plants and some people feel they have a flavor very similar to regular sugar. The FDA says these sweeteners are “generally regarded as safe,” which means they are safe to use for their intended purpose.

What is the healthiest sugar substitute? ›

Stevia and monk fruit are both naturally derived from plants and some people feel they have a flavor very similar to regular sugar. The FDA says these sweeteners are “generally regarded as safe,” which means they are safe to use for their intended purpose.

Does sucralose ruin gut health? ›

Altered gut bacterial genera were associated with the saccharin-induced liver inflammation. No effects on gut microbiota. No effects on gut microbiota. The consumption of sucralose decreased the total anaerobes and aerobic bacteria, bifidobacteria, lactobacilli, Bacteroides, and Clostridium.

Is stevia better than sucralose? ›

Stevia also appears safe for almost everyone if consumed at sensible levels, whereas sucralose may contribute to blood sugar/ insulin rises and may also negatively affect your gut health with regular consumption.

Why is stevia banned in Europe? ›

Stevia was initially banned because some highly alarming early studies suggested that the sweetener might be linked to cancer. There were also other concerns about the sweet compounds in stevia leaves, known as steviol glycosides.

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